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Recruitment: development of the genome editing platform

SIRIC team
09/04/2018
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A key post for multiple projects of the SIRIC program
Equipe CRISPR-Cas9, plateforme CRISPR'it

A position for a biology engineer specialized in the development of genome editing tools is open at the Institut Curie Research Centre. The candidate will work in close collaboration with the CRISPR’it platform under the scientific supervision of Raphaël Margueron (Genetics and Developmental Biology Unit).

Context

Institut Curie is a major player in cancer treatment and research. Composed of both a Hospital and a Research Center, Institut Curie’s expertise extends from basic research to patient care. The objective of the Institut Curie Research Center is to develop basic research and use this knowledge to improve diagnosis, prognosis and cancer treatment as part of the continuum between basic research and innovation at the service of the patient.

Missions

Genome editing tools have facilitated the recent developments in genetic screening on mammal cells. These tools are particularly promising for research on synthetic lethality and the identification of altered signal pathways in cancer.

The objective of the biology engineer will be to develop the conditions of these techniques “in vivo”. Many optimizations will be necessary to achieve this goal.

Required profile

In possession of an engineering degree or a master’s degree in biology you have the following skills:

  • Expertise in cell culture and molecular biology
  • Knowledge of viral tools for distributing gRNA libraries
  • Creative and enterprising spirit
  • Good level of written and oral English
  • Good communication skills, organized and conscientious

Constraints

  • Work in a confined environment
  • Work with viruses
  • Working with mouse models

Place of work: Paris (5th arrondissement)

Remuneration: depending on profile and experience

Send your application (CV, cover letter and references) by email to ao.siric@curie.fr, deadline 30 September 2018.