ChromSCape: a tool for interactive analysis of chromatin profiles at a single cell level | Integrated Cancer Research Site

The development of "single cell" analysis tools is in the process of revolutionizing cancer research. This technique requires specific tools to manage the data.

The Single Cell platform at Institut Curie, supported by the SIRIC since its creation, has been developing these tools. In this frame, Prompsy et al propose ChromSCape: a user-friendly Shiny application.

This tool facilitates biological interpretation of epigenomic landscpaes within cell populations and allows the user to identify different sub populations in heterogenous samples as well as genes and associated pathways.

Our single cell projects: further reading

La plateforme single cell à l'Institut Curie

Uriel Chantraine / Institut Curie

L'analyse de cellules uniques au coeur du programme SIRIC

Une action structurante ouvrant la voie à de nombreuses applications

Signature épigénétique associée à la résistance aux traitements dans le cancer du sein

Collaboration entre 3 équipes pour développer une technique d'analyse de cellules uniques

Epigénétique, ADN

Nicolas Bouvier

Plasticité épigénétique

Exploitation d'une approche single cell haut débit pour suivre l'évolution des tumeurs avant et pendant les traitements

Read the Prompsy et al. article

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