The SIRIC budget is not intended to fund all of the costs of SIRIC projects. It’s an addition to other budget sources and has an important leverage effect. In allowing us to fund key posts or essential missing structures it benefits all teams well beyond the remit of SIRIC projects and accelerates the development of integrated cancer research at the heart of Institut Curie.
Support of integrated research programs
Mutualized key posts: an essential element of integration
The SIRIC budget supports scientific projects via mutualized key posts. These posts are essential for inter-program integration. The posts are engineers, managers, clinical research assistants or post-doctoral researchers.
We also fund part of the programs via a laboratory functioning budget essentially for the development of preclinical models and high throughput DNA sequencing.
Technological and transverse structures for the programs
The platforms at Institut Curie are essential for the development of SIRIC research programs but are also at the heart of translational research. SIRIC funding also benefits a large number of teams far beyond the SIRIC scientific program.
We support the following platforms in particular:
- CRISPR for functional studies
- Single cell for tumor heterogeneity or clonality studies as well as immunotherapy projects
- NGS (next generation sequencing) for genetic and epigenetic analyses by high throughput DNA sequencing
- BioPhenics for robotic cell screening (high throughput)
- LIP (preclinical investigation laboratory) for projects needing to work on preclinical models
- Pathology for sampling analysis and the organization of sampling circuits
- Pathex (experimental pathology) for tissue analysis in preclinical research projects
SIRIC support is materialized by funding manager or engineer positions.
Emergence of new projects
The implication of clinician-researchers in translational research is a major challenge. SIRIC helps us to attract new talents and develop new projects. We plan to create a new translational research team in radiotherapy. This team will be at the interface of care and research and will interact with the whole care-research ecosystem and, in particular, the teams created during the first SIRIC endorsement.
Support of health democracy development
We have a significant budget to set up a health democracy project which will cover communication but also travel or invitation of experts in the sphere of health democracy. We also have a human resources budget to establish new research projects.