Focus on relapse
Despite considerable progress in cancer treatment over the past decades, relapse after the initial treatment response is still a major challenge.
Whether local or distant from the initial site, disease recurrence is primarily associated with treatment resistance.
A better understanding of the mechanisms behind cancer relapse is essential to being able to anticipate relapse, prevent it, detect it as early as possible and treat it effectively. These are essential objectives to improve patient care and definitively eradicate the disease.
To this end, we are developing 3 integrated research programs by addressing the issue of recidivism at 3 levels:
1. Cellular: intrinsic mechanisms of recurrence
coordinated by Céline Vallot and Yves Allory
2. Tissular : extrinsic mechanisms of recurrence
coordinated by Hélène Salmon and Manuel Rodrigues
3. Whole organism: detection and treatment of relapse
coordinated by Elisabetta Marangoni and François-Clément Bidard
Whether local or distant from the initial site, disease recurrence is primarily associated with treatment resistance.
A better understanding of the mechanisms behind cancer relapse is essential to being able to anticipate relapse, prevent it, detect it as early as possible and treat it effectively. These are essential objectives to improve patient care and definitively eradicate the disease.
To this end, we are developing 3 integrated research programs by addressing the issue of recidivism at 3 levels:
1. Cellular: intrinsic mechanisms of recurrence
coordinated by Céline Vallot and Yves Allory
2. Tissular : extrinsic mechanisms of recurrence
coordinated by Hélène Salmon and Manuel Rodrigues
3. Whole organism: detection and treatment of relapse
coordinated by Elisabetta Marangoni and François-Clément Bidard
The actors
The coordinators
Each program is piloted by a pair